Photomicrographs demonstrating the impact of T lymphocytes (T cells) associated with the intestinal disease necrotizing enterocolitis (NEC) on myelin — a fatty material that surrounds and protects nerve cells — in laboratory-grown mouse brain organoids (“mini-brains”) that model the brain of a premature human infant. The left image shows brain organoids from healthy mice with numerous myelin connections between the neurons (bright areas). The right image shows brain organoids exposed to T cells from mice with NEC displaying a distinct reduction in the number of myelin fibers connecting neurons. Credit: C. Zhou, C. Sodhi and D. J. Hackam, Johns Hopkins Medicine

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Mouse study finds link between gut disease and brain injury in premature infants

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